J. Smieja (Poland)
Modelling, viral infection, signalling pathways
This work presents a novel, two-scale model of viral
infection evolution in a cell population taking into
account immunological response based on Interferon-β.
Infection dynamics is analyzed on a population level,
using standard compartmental approach and on a
intracellular level, describing biochemical processes
taking place inside cells during infection. Additionally, an
optimization problem has been stated, aiming at finding
best therapy protocols using Interferon-β.