R. Roche, R. Lamanna, M. Delgado, F. Rocaries (Venezuela), Y. Hamam, and F. Pecker (France)
Cardiac simulation, Cardiac cell, E-C coupling, Calcium
dynamics, Cellular simulation.
A simulator of the cardiac cell (E-C coupling process) is
developed which solves the electro-chemical model of the
cell proposed by Roche et al. . It also contains the
models by Tang and Othmer , Luo and Rudy  and
Fox , for comparison purposes. The simulator allows
modifications of the model parameters in correspondence
with the different cellular elements, to emulate cells of
different species or cells under different conditions. Hence
it can be used for testing the sensibility of the E-C process
to drugs and inhibitors and is intended as a research tool in
experiment design and cardiac pathology treatment.