Modeling and Realization of the Human Growth Hormone Secretion Mechanism using VHDL and FPGAs

N. Botros, A. Akaaboune, and J. Alghazo (USA)


Human Growth Hormone (HGH), VHDL, FieldProgrammable Gate Arrays (FPGAs), System on Chip(SoC), Modeling and Realization.


In this paper we present a hardware realization of a simplified Human Growth Hormone (HGH) secretion mechanism. The mechanism is developed into a flowchart and then modeled using Hardware Descriptive Language (HDL). HDL behavioral modeling is implemented to simulate the behavior of the mechanism on the computer's screen. After verifying the simulation results, Computer Aided Design (CAD) tools are used to synthesize the mechanism onto Xilinx FPGAs chip. The chip is tested by inputting signals with values corresponding to the concentration of GHRH and the concentration of SRIF. A user-selected output pins on the chip show the concentration of HGH and the concentration of IGF-I. The outputs are compared with those generated by the simulation. Both the simulation and the chip generate identical patterns. We conclude that the chip mimics the HGH mechanism. The chip after synthesize is a stand-alone system that does not need a computer for operation. The chip operates on a real time basis.

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