Using Artificial Neural Networks to Model Acoustic Release of Doxorubicin from Unstabilized Pluronic P105

G. Husseini (UAE, USA), N.M. Abdel-Jabbar (UAE, Jordan), F.S. Mjalli (Malaysia), and W.G. Pitt (USA)

Keywords

Neural network modeling, ultrasound, micelles, polymeric carriers, nonlinear modeling.

Abstract

Acoustically activated drug release from unstabilized Pluronic P105 micelles was modeled using an Artificial Neural Network Model. Sensitivity analysis revealed that optimal conditions are achieved at low frequency and high power densities.

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