J. Smieja (Poland)
Modelling, viral infection, signalling pathways
This work presents a novel, two-scale model of viral infection evolution in a cell population taking into account immunological response based on Interferon-β. Infection dynamics is analyzed on a population level, using standard compartmental approach and on a intracellular level, describing biochemical processes taking place inside cells during infection. Additionally, an optimization problem has been stated, aiming at finding best therapy protocols using Interferon-β.
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