Signal Analysis in a New Optical Pulse Waveform Profiler for Cardiovascular Applications

Tânia Pereira, Tatiana Oliveira, Manuel Cabeleira, Patrícia Matos, Helena C. Pereira, Vânia Almeida, Elisabeth Borges, Helder Santos, Telmo Pereira, João Cardoso, and Carlos Correia


Signal Reconstruction, Digital Signal Processing, Optical System


Sub-millimetre distension waveforms (0.7 mm, max) are assessed using two new optical probes. The probes differ on the type of photo-detector used: planar photodiodes (PPD), in one case, and avalanche photodiodes (APD), in the other. Performance of the probes is evaluated in an especially developed test setup and in vivo, at the carotid site of humans. In the latter case, distension (associated to the pressure wave generated by the left ventricle contraction that propagates through the arterial system) carries clinically relevant information that can be extracted if, as will be shown, the waveforms are accurate and have enough resolution. An ultrasound image system, VividTM e, was used as source of reference data for comparison. Along with the probes, a set of software routines was also developed to extract artefact-free data and evaluate the error. Results from the test setup demonstrate the possibility of waveform distension measurements with less than 6% error for both optical probes in this study. In comparison with an ultrasound system, the optical sensors allow the reproduction of the arterial waveform with a higher resolution, adequate to feed feature extraction algorithms.

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