Bending Properties of a Bone Glue Containing Polymethylmethacrylate and Hydroxyapatite and Gelatin

Taymaz Jozaghi, Nazanin Afsar Kazerooni, Mohammad Ebrahim Bahrololoom, Mohammad Hossein Shariat, and Fatemeh Mahzoon


Bone Glue, Methyl Methacrylate, Hydroxyapatite, Gelatin, Bending Strength


The use of bone glue has become increasing frequent due to its advantages and conveniences. Poly Methyl Methacrylate (PMMA) has been used for a long time as bone cements and bone glues, but it is not the best option due to its biocompatibility. Therefore, different kinds of composites have been invented. Hydroxyapatite (HA), which is a main ingredient in the hard tissues of the body, has shown promising applications in biomedical implants. Gelatin also, being a collagen, could enhance the biocompatibility. In this paper, a composite bone glue was designed by mixing PMMA and HA and gelatin. The bending strength of this glue was measured and compared with PMMA glue. Fractions of bones were reattached using these glues, and were kept in ambient atmosphere and in Ringer’s solution for 24 hours. Then bending tests were carried out and the bending strength was measured. The surfaces of the fracture were studied using a Scanning Electron Microscope (SEM). The results indicated that though the bending strength of the composite glue was less than that of the PMMA glue due to the presence of the ceramic (HA) particles, the composite glue has lower polymerization temperature and as a results of the presence of the HA and gelatin particles, it has a rougher surface which in turn may lead to a better bone healing.

Important Links:

Go Back