Consistent Quasi-Static and Ultrasonic Elasticity Determination of PLLA-based Rapid-Prototyped Tissue Engineering Scaffolds

Krzysztof W. Luczynski, Tomasz Brynk, Barbara Ostrowska, Wojciech Swieszkowski, Roland Reihsner, and Christian Hellmich


Biomechanics, Biomaterials, Elasticity, Tissue Engineering Scaffolds


This paper is concerned with the elasticity determination of rapid-prototyped tissue engineering scaffolds made of poly-l-lactide (PLLA) with tricalcium phosphate (TCP) inclusions. At the level of overall scaffolds, i.e. that of several millimeters, multiple uniaxial loading-deloading tests were performed, giving access to the scaffolds’ Young’s moduli. Additionally, acoustic tests with 0.05Mhz frequency delivered an independent access to elastic properties, in terms of the normal components of the scaffolds’ stiffness tensors. The latter strongly correlate in a linear fashion, with the Young’s moduli from the deloading tests, revealing porosity-independence of Poisson’s ratio. The magnitude of the latter is in full agreement with literature data on polymers. Both of these facts reassure the choice of used methods to reliably measure elasticity of tissue engineering scaffolds.

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