Is Cell Cycle a Perfect Fault Tolerant Control System? – System Engineering Point of View

Andrzej Swierniak, Roman Jaksik, and Jaroslaw Smieja


Cell cycle, DNA damage repair, fault prone systems, p53 regulatory module


We present a system engineering approach to a problem of DNA damage-repair in human cells. We discuss chosen control systems existing in the cells and demonstrate that they constitute an almost perfect fault tolerant system. We discuss the consequences of gaps in this system and explain why it cannot be completely perfect.

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